For a full list of Publications please visit PubMed
Highlighted Publications
- Bone Relat RM, Winder PL, Bowden GD, Guzmán EA, Peterson TA, Pomponi SA, Roberts JC, Wright AE, O'Connor RM. High-Throughput Screening of a Marine Compound Library Identifies Anti-Cryptosporidium Activity of Leiodolide A. Mar Drugs. 2022 Mar 30;20(4). doi: 10.3390/md20040240. PubMed PMID: 35447913; PubMed Central PMCID: PMC9026894.
- Gallego-Lopez GM, Mendoza Cavazos C, Tibabuzo Perdomo AM, Garfoot AL, O'Connor RM, Knoll LJ. Dual Transcriptomics To Determine Gamma Interferon-Independent Host Response to Intestinal Cryptosporidium parvum Infection. Infect Immun. 2022 Feb 17;90(2):e0063821. doi: 10.1128/iai.00638-21. Epub 2021 Dec 20. PubMed PMID: 34928716; PubMed Central PMCID: PMC8852703.
- Abenoja J, Cotto-Rosario A, O'Connor R. Boromycin Has Potent Anti-Toxoplasma and Anti-Cryptosporidium Activity. Antimicrob Agents Chemother. 2021 Mar 18;65(4). doi: 10.1128/AAC.01278-20. Print 2021 Mar 18. PubMed PMID: 33468470; PubMed Central PMCID: PMC8097477.
- Bowden GD, Reis PM, Rogers MB, Bone Relat RM, Brayton KA, Wilson SK, Di Genova BM, Knoll LJ, Nepveux V FJ, Tai AK, Ramadhar TR, Clardy J, O'Connor RM. A conserved coccidian gene is involved in Toxoplasma sensitivity to the anti-apicomplexan compound, tartrolon E. Int J Parasitol Drugs Drug Resist. 2020 Dec;14:1-7. doi: 10.1016/j.ijpddr.2020.07.003. Epub 2020 Jul 25. PubMed PMID: 32738587; PubMed Central PMCID: PMC7394737.
- Relat RMB, O'Connor RM. Cryptosporidium: host and parasite transcriptome in infection. Curr Opin Microbiol. 2020 Dec;58:138-145. doi: 10.1016/j.mib.2020.09.012. Epub 2020 Nov 4. Review. PubMed PMID: 33160225.
- RM O’Connor, FJ Nepveux V, J. Abenoja, G. Bowden, P. Reis, J. Beaushaw, R. Relat, I. Driskell, F. Gimenez, M.W. Riggs, D. A. Schaefer, E.W. Schmidt, Z. Lin, D.L. Distel, J. Clardy, T. Ramadhar, D.R. Allred, H. Fritz, P. Rathod, L. Chery, J. White. A symbiotic bacterium of shipworms produces a compound with broad spectrum anti-apicomplexan activity. PloS Pathogens. 16(5):e1008600. https://doi.org/10.1371/journal.ppat.1008600
- Heo I, Dutta D, Schaefer DA, Iakobachvili N, Artegiani B, Sachs N, Boonekamp KE, Bowden G, Hendrickx APA, Willems RJL, Peters PJ, Riggs MW, O'Connor RM, Clevers H. Modelling Cryptosporidium infection in human small intestinal and lung organoids. Nat Microbiol. 2018 Jul;3(7):814-823. doi: 10.1038/s41564-018-0177-8. Epub 2018 Jun 25.
- O'Connor RM, Fung JM, Sharp KH, Benner JS, McClung C, Cushing S, Lamkin ER, Fomenkov AI, Henrissat B, Londer YY, Scholz MB, Posfai J, Malfatti S, Tringe SG, Woyke T, Malmstrom RR, Coleman-Derr D, Altamia MA, Dedrick S, Kaluziak ST, Haygood MG, Distel DL. Gill bacteria enable a novel digestive strategy in a wood-feeding mollusk. Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):E5096-104.
- O'Connor RM*, Burns PB, Ha-Ngoc T, Scarpato K, Khan W, Kang G, Ward H. Polymorphic mucin antigens CpMuc4 and CpMuc5 are integral to Cryptosporidium parvum infection in vitro. Eukaryot Cell. 2009 Apr;8(4):461-9. doi: 10.1128/EC.00305-08. Epub 2009 Jan 23. PubMed PMID: 19168754; PubMed Central PMCID: PMC2669191.
- O'Connor RM, Allred DR. Selection of Babesia bovis-infected erythrocytes for adhesion to endothelial cells coselects for altered variant erythrocyte surface antigen isoforms. J Immunol. 2000 Feb 15;164(4):2037-45. doi: 10.4049/jimmunol.164.4.2037. PubMed PMID: 10657656